ABSTRAK

Pengaruh Self efficacy dan Kepatuhan Minum Obat Terhadap Kualitas Hidup
Pasien Tuberculosis paru di Klinik Paru RSUD Bumiayu Tahun 2025

Florent Charisma1, Aziez Ismunandar2, Luthfi Hidayat Maulana3.
Program Studi Farmasi
Fakultas Sains dan Tekhnologi
Universitas Peradaban
E-mail:  florentcharisma064@gmail.com

Tuberculosis paru merupakan penyakit menular yang masih menjadi permasalahan pada angka kejadian, kematian, maupun diagnosis dan terapinya disebabkan oleh mycobacterium tuberculosis yang menyerang parenkim paru. Tuberculosis paru merupakan penyakit yang membutuhkan terapi jangka panjang selama 2-12 bulan atau lebih secara rutin, disiplin, tanpa terputus yang dapat menyebabkan perubahan pada kualitas hidup pasien tuberculosis. Self efficacy dan kepatuhan minum obat menjadi faktor penting terhadap kualitas hidup pasien tuberculosis paru. Tujuan penelitian ini adalah untuk mengetahui pengaruh self  efficacy (TBSES21) dan kepatuhan minum obat (MMAS-8) terhadap kualitas hidup (WHOQOL-BREFF) pasien tuberculosis paru di Klinik Paru RSUD Bumiayu Tahun 2025. Penelitian ini merupakan  jenis penelitian kuantitatif dengan  metode  cross sectional.  Jumlah populasi pada penelitian ini adalah pasien tuberculosis paru yang menjalankan pengobatan di klinik paru RSUD Bumiayu tahun 2024, dan sampel diambil menggunakan total sampling yakni 79 pasien. Analisa dilakukan dengan menggunakan uji t dan regresi linear berganda. Hasil penelitian self efficacy menunjukan nilai signifikansi < 0,05 (yakni 0,025) dan t hitung (5,423) > t tabel (1,9917), yang berarti terdapat pengaruh self efficacy terhadap kualitas hidup pasien tuberculosis paru. Dan hasil penelitian kepatuhan minum obat menunjukan nilai signifikansi < 0,05 (yakni 0,000) yang berarti terdapat pengaruh kepatuhan minum obat terhadap kualitas hidup pasien tuberculosis paru. Hasil analisis regresi linear berganda dengan nilai R square 30% yang dapat diambil kesimpulan bahwa terdapat pengaruh self efficacy dan kepatuhan minum obat terhadap kualitas hidup pasien tuberculosis paru di Klinik Paru RSUD Bumiayu Tahun 2025.

Kata Kunci: Tuberculosis paru, Self efficacy, Kepatuhan minum obat, Kualitas hidup

ABSTRACT

The Influence of Self-Efficacy and Medication Adherence on the Quality of Life of Pulmonary Tuberculosis Patients at the Pulmonology Clinic of Bumiayu Regional General Hospital in 2025

Florent Charisma1, Aziez Ismunandar2, Luthfi Hidayat Maulana3.
Pharmacy Study Program Faculty of Science and Technologyy Peradaban University
E-mail: florentcharisma064@gmail.com

Pulmonary tuberculosis (TB) is a contagious disease that continues to be a problem in terms of incidence, mortality, diagnosis, and therapy. It is caused by Mycobacterium tuberculosis, which attacks the lung parenchyma. Pulmonary TB requires long-term therapy for 2-12 months or more, which must be taken regularly, disciplined, and without interruption. This can lead to changes in the quality of life for TB patients. Self-efficacy and medication adherence are important factors affecting the quality of life of pulmonary TB patients. The purpose of this study was to determine the effect of self-efficacy (TBSES21) and medication adherence (MMAS-8) on the quality of life (WHOQOL-BREFF) of pulmonary TB patients at the Lung Clinic of Bumiayu Regional Hospital in 2025. This was a quantitative study using a cross-sectional method. The study population included pulmonary TB patients undergoing treatment at the Lung Clinic of Bumiayu Regional Hospital in
2024. The sample was collected using a total sampling method, which included 79
patients. The analysis was conducted using a t-test and multiple linear regression. The results for self-efficacy showed a significance value of < 0.05 (specifically,
0.025) and a t-count (5.423) > t-table (1.9917), which indicates that self-efficacy has an effect on the quality of life of pulmonary TB patients. The results for
medication adherence showed a significance value of < 0.05 (specifically, 0.000), which indicates that medication adherence has an effect on the quality of life of
pulmonary TB patients.The results of the multiple linear regression analysis with an R-squared value of 30% conclude that there is an effect of both self-efficacy and medication adherence on the quality of life of pulmonary TB patients at the Lung Clinic of Bumiayu Regional Hospital in 2025.

Keywords: Pulmonary tuberculosis, Self-efficacy, Medication adherence, Quality of life